New York Giants @ Tampa Bay Buccaneers (8:15 p.m. ET, ESPN)
Point spread: Buccaneers -11 (Buccaneers favored to win by more than 11 points, otherwise Giants cover)
Total scoring over/under: 49.5 points scored by both teams combined
Monday's contest will make it five consecutive seasons the teams have played each other, a rarity among non-divisional foes. They split the previous four games but the Giants lead the all-time series 16-9.
Tampa Bay enters the contest on a two-game losing streak. The last time Tom Brady lost three straight games?
Brady continues to defy time as the 44-year-old quarterback is fifth in the NFL in passing yardage with 2,870, but Brady has played one or two fewer games than the four QBs ahead of him.
Brady is 254-for-377 passing (67.4 percent) with 27 touchdown passes and seven interceptions.
Brady leads the NFL in passing yards per game with 318.9 but faces a Giants defense that has an interception in six consecutive games, the longest active streak in the NFL.
Jones is 190-for-293 passing (64.8 percent) for 2,059 yards, eight touchdowns and five interceptions.
Jones adds another dimension over Brady with 258 rushing yards, fifth among quarterbacks, with two touchdowns.
Jones and the Giants hope to get a boost with the return of running back Saquon Barkley. The No. 2 pick in 2018 has missed four games with an ankle injury but returned to practice and is expected to play.
Jones has completed passes to 10 different players this season, including standout rookie receiver Kadarius Toney (28 catches for 352 yards).
But the Giants struggle finishing off drives. They have scored a touchdown on 11 of 25 (44 percent) of their red zone trips this season, the lowest percentage in the NFL.
The Giants are 0-5 in their past 5 Monday Night Football games, including a 20-17 loss to the Kansas City Chiefs on Nov. 1.
The Giants have been favored only once this season (-2.5 against the Atlanta Falcons on Sept. 26, a 17-14 loss).
The Giants are 5-4 against the spread (ATS) this season.
The Buccaneers are 3-6 ATS.
The Buccaneers are 4-0 at home this season.
Brady is 18-8 in 26 career Monday Night Football starts.
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