DEA agents seized over 13 points of a heroin/fentanyl blend with a street value of nearly $2 million.
The narcotics were headed for distribution throughout New York City and Massachusetts.
Diego Tejada-Rosario and Victor Camacho were arrested in Fordham Manot after an investigation.
Both have been charged with criminal possession of a controlled substance and criminal use of drug paraphernalia.
Tejada has previously been charged with drug-related offenses in early 2020, but due to bail reforms, was released on supervised release, according to the DEA.