It happened Thursday just after 2 p.m. at the Puffume Smoke Shop located at 43-45 44 St. in the Sunnyside section.
According to police, the two men entered the location and pointed a gun at the employee.
The men then removed store merchandise valued at $10,500 before fleeing in a white 2014 Honda Accord, with a New York license plate, traveling southbound on 44 St., police said.
No injuries were reported.
Description of the individuals
The first individual is described as a man with dark complexion, thin build, last seen wearing a black face mask, blue hooded sweatshirt, black backpack, pink gloves, black pants and black shoes. He was in possession of a firearm.
The second individual is described as a man with dark complexion, thin build, large black hair, last seen wearing a white face mask, black t-shirt, black gloves and black pants.
Anyone with information is asked to call the NYPD's Crime Stoppers Hotline at 1-800-577-TIPS (8477).