"Breaking the tape at this year's Boston Marathon was a lifelong dream come true," Linden said in a news release. "At the moment, it felt like it was the culmination of my career, but I believe I still have plenty more to give to the marathon."
Linden, 34, represented the United States in the 2012 Olympic marathon in London (but dropped out due to injury) and in the 2016 Olympic marathon in Rio, where she finished seventh.
She has run the New York City Marathon once before, in 2014, when she finished fifth.
In April, Linden's win at the Boston Marathon on a cold and wet day ended a 33-year drought for American runners in the women's open division. Her victory highlighted a strong day for U.S. women, who took seven of the top eight slots in that race.
"New York Road Runners has a great history with Des and we're excited to welcome her back to the TCS New York City Marathon," Peter Ciaccia, the marathon's race director, said in a news release. "Her win in Boston continued to shine the spotlight on an incredibly talented group of elite women in the U.S. and around the world."
With around 50,000 finishers in recent years, the TCS New York City Marathon is the largest marathon in the world. This year's race through the five boroughs race is set for Sunday, November 4.